| Date | Location | Result | |
| 03/18/12 | Norfolk, Va. (Scope Arena) | Old Dominion 65, USC Upstate 56 | Box score |
| 03/15/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 73, Kent State 58 | Box score |
| 03/01/12 | Macon, Ga. (University Center) | Florida Gulf Coast 71, USC Upstate 61 | Box score |
| 02/25/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 90, Stetson 72 | Box score |
| 02/23/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 87, Florida Gulf Coast 74 | Box score |
| 02/20/12 | Nashville, Tenn. (Curb Event Center) | Belmont 88, USC Upstate 79 | Box score |
| 02/18/12 | Nashville, Tenn. (Allen Arena) | USC Upstate 62, Lipscomb 61 | Box score |
| 02/13/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 77, North Florida 52 | Box score |
| 02/11/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 70, Jacksonville 66 | Box score |
| 02/06/12 | Kennesaw, Ga. (KSU Convocation Center) | USC Upstate 70, Kennesaw State 58 | Box score |
| 02/04/12 | Macon, Ga. (University Center) | Mercer 61, USC Upstate 47 | Box score |
| 01/30/12 | Jacksonville, Ala. (Pete Mathews Col.) | USC Upstate 82, Jacksonville State 77 | Box score |
| 01/27/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 58, ETSU 54 | Box score |
| 01/23/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 61, Lipscomb 52 | Box score |
| 01/21/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 79, Belmont 78 | Box score |
| 01/16/12 | Jacksonville, Fla. (Swisher Gymnasium) | Jacksonville 77, USC Upstate 74 | Box score |
| 01/14/12 | Jacksonville, Fla. (UNF Arena) | USC Upstate 69, North Florida 62 | Box score |
| 01/09/12 | Spartanburg, S.C. (Hodge Center) | Mercer 73, USC Upstate 66 | Box score |
| 01/07/12 | Spartanburg, S.C. (Hodge Center) | USC Upstate 68, Kennesaw State 53 | Box score |
| 01/04/12 | Johnson City, Tenn. (MSHA Ath. Center) | ETSU 88, USC Upstate 73 | Box score |
| 12/31/11 | Columbia, S.C. (Colonial Life Arena) | South Carolina 72, USC Upstate 66 | Box score |
| 12/19/11 | Fort Myers, Fla. (Alico Arena) | USC Upstate 80, Florida Gulf Coast 75 | Box score |
| 12/17/11 | DeLand, Fla. (Edmunds Center) | USC Upstate 79, Stetson 63 | Box score |
| 12/14/11 | Columbus, Ohio (Value City Arena) | Ohio State 82, USC Upstate 58 | Box score |
| 12/11/11 | Dayton, Ohio (UD Arena) | Dayton 72, USC Upstate 68 | Box score |
| 12/04/11 | Asheville, N.C. (Kimmel Arena) | UNC Asheville 88, USC Upstate 81 | Box score |
| 12/01/11 | Spartanburg, S.C. (Hodge Center) | USC Upstate 50, Jacksonville State 48 | Box score |
| 11/27/11 | Spartanburg, S.C. (Hodge Center) | USC Upstate 88, Victory University 54 | Box score |
| 11/25/11 | Spartanburg, S.C. (Hodge Center) | USC Upstate 78, Texas-Pan American 63 | Box score |
| 11/20/11 | Edinburg, Texas (UTPA Fieldhouse) | USC Upstate 82, Texas State 74 | Box score |
| 11/19/11 | Edinburg, Texas (UTPA Fieldhouse) | Toledo 75, USC Upstate 70 | Box score |
| 11/18/11 | Edinburg, Texas (UTPA Fieldhouse) | USC Upstate 70, Texas-Pan American 66 | Box score |
| 11/14/11 | Spartanburg, S.C. (Hodge Center) | USC Upstate 91, Piedmont College 66 | Box score |
| 11/11/11 | Fayetteville, Ark. (Bud Walton Arena) | Arkansas 83, USC Upstate 63 | Box score |